一、研究方向 生物物理、生物信息学、信号与信息处理 二、主持完成的主要科研项目 1. 国家自然科学基金，蛋白质亚线粒体定位及其特征信息和预测算法的挖掘，2015-2018 2． 内蒙古自然科学基金，蛋白质亚线粒体定位预测及其算法研究，2013-2015 3． 内蒙古自治区高等学校科学研究项目，蛋白质亚线粒体定位预测及相关生物学功能关系，2013-2014 4． 澳门第一娱乐娱城官网高层次人才引进科研启动项目，基于信息融合的蛋白质亚线粒体定位预测算法研究，2014-2015 5． 澳门第一娱乐娱城官网青年基金，基于平均化学位移的蛋白质二级结构预测，2009-2010 6． 资助研究生科研项目，基于平均化学位移的蛋白质结构域预测研究，2009-2011 7． 参与，抗冻蛋白在冰晶表面吸附结合的机制及其对冰晶生长行为影响的研究，2012-2015 三、目前的主要研究方向 1．表观遗传修饰与疾病相关研究 2．蛋白质亚细胞定位、亚线粒体定位预测及其生物学功能关系 四、目前主持的主要科研项目 1． 国家自然科学基金，基于表观遗传修饰数据的肾癌生物标记物挖掘，2021-2024 2． 内蒙古自治区高等学校科学研究项目，利用表观遗传修饰数据挖掘肾癌生物标记物，2020-2022 五、主要论著 1. 彭宝成, 张晓炜*，刘暘,樊国梁*. 基于CNN 的大肠杆菌启动子预测. Prog. Biochem. Biophys. 2021, 48(12): 1136-1143 (SCI) 2. 顾佳欣, 于海青,樊国梁*.头颈部鳞状细胞癌差异表达基因分析. 澳门第一娱乐娱城官网学报(自然科学版), 2021, 52 (02):52 60. 3. 于海青, 顾佳欣,樊国梁*.宫颈癌分子调控机制的关键基因分析. 澳门第一娱乐娱城官网学报(自然科学版), 2021, 52 (01):49 58. 4. Zhang LQ, Fan GL, Liu JJ, Liu L, Li QZ* and Lin H*. Identification of Key Histone Modifications and Their Regulatory Regions on Gene Expression Level Changes in Chronic Myelogenous Leukemia. Frontiers in Cell and Developmental Biology. 2021, 8:1735 5. Wang H, Liu Y and Fan GL*. The Regulation of target genes by co-occupancy of transcription factor c-Myc, Mxi1 with Max in the mouse cell line. Current Bioinformatics, 2020, 15(6):547-555. (SCI) 6. Wu CY*, Li QZ, Xing R, Fan GL. Using the Chou’s Pseudo Component to Predict the ncRNA Locations Based on the Improved K-nearest Neighbor (iKNN) Classifier. Current Bioinformatics. 2020, 15(6): 582 – 592. (web server) 7. Liu F, Liu Y, Wang H, Fan GL*. Identification of survival and main function in kidney renal clear cell carcinoma, Basic Clinical Pharmacology Toxicology, 2019, 137(s1):87-88. (SCI) 8. Wang H, Liu YL, Liu Y, Yan X, Fan GL*, Zhang XW. The correlation between co-occupancy patterns of transcription factors with histone modification and dnase i in the mouse cell line, Basic Clinical Pharmacology Toxicology, 2018, 123(s1):82-83(SCI) 9. Fan GL*, Liu YL, Wang H. Identification of thermophilic proteins by incorporating evolutionary and acid dissociation information into Chou's general pseudo amino acid composition. J. THEOR. BIOL., 2016, 407(2016):138–142. (SCI) 10. Su WX, Li QZ, Zhang LQ, Fan GL, Wu CY, Yan ZH. Gene expression classification using epigenetic features and DNA sequence composition in the human embryonic stem cell line H1. Gene, 2016:227-234. (web server) 11. Fan GL*, Zhang XY, Liu YL, Nang Y, Wang H. DSPMP: Discriminating Secretory Proteins of Malaria Parasite by Hybridizing Different Descriptors of Chou’s Pseudo Amino Acid Patterns. J. Comput. Chem. 2015, 36：2317–2327(SCI) (web server) 12. 曩毅,梅含雪,赵燕,侯宝妍,赵志远,樊国梁*. 基于Blast GO 的蛋白质亚线粒体定位预测. Prog. Biochem. Biophys. 2015, 42(12): 1136-1143 (SCI) 13. Zuo YC*, Lv Y, Wei ZY, Yang L, Li GP, Fan GL*, iDPF-PseRAAAC: A Web-Server for Identifying the Defensin Peptide Family and Subfamily Using Pseudo Reduced Amino Acid Alphabet Composition. PLOS ONE, 2015, 10(12): e0145541. (web server) 14. Fan GL*, Liu YL, Zuo YC*, Mei HX, Rang Y, Hou BY, Zhao Y, acACS: Improving the Prediction Accuracy of Protein Subcellular Locations and Protein Classification by Incorporating the Average Chemical Shifts Composition. The Scientific World Journal, 2014, 2014, ID 864135: 9 pages (SCI) (web server) 15. Zuo YC*, Peng Y, Liu L, Chen W, Yang L, Fan GL*, Predicting peroxidase subcellular location by hybridizing different descriptors of Chou’ pseudo amino acid patterns. Anal BioChem, 2014, 458(2014):14-19 (SCI) 16. Fan GL*, Li QZ, Zuo YC, Predicting acidic and alkaline enzymes by incorporating the average chemical shift and gene ontology informations into the general form of Chou's PseAAC[J]. Process Biochemistry, 2013,48(7):1048–1053.(SCI) (web server) 17. Fan GL*, Li QZ, Discriminating bioluminescent proteins by incorporating average chemical shift and evolutionary information into the general form of Chou's pseudo amino acid composition [J]. J. THEOR. BIOL., 2013, 334(2013):45–51.(SCI) 18. Li T, Li QZ, Liu S, Fan GL, Zuo YC, Peng Y, PreDNA: accurate prediction of DNA-binding sites in proteins by integrating sequence and geometric structure information, Bioinformatics, 2013, 29(2013):678-685(SCI) (web server) 19. Zuo YC, Chen W, Fan GL, Li QZ, A similarity distance of diversity measure for discriminating mesophilic and thermophilic proteins. Amino Acids, 2013, 44(2013):573-580 (SCI) (web server) 20. Fan GL*, Li QZ, Predicting protein submitochondria locations by combining different descriptors into the general form of Chou's pseudo amino acid composition. [J].Amino Acids, 2012, 43(2012):545–555 (SCI) (web server) 21. Fan GL*, Li QZ, Predict mycobacterial proteins subcellular locations by incorporating pseudo-average chemical shift into the general form of Chou's pseudo amino acid composition.[J]. J. THEOR. BIOL., 2012, 304(2012):88–95.(SCI) (web server) 22. Fan GL*, Li QZ, Yang KL, TFBSs: a web server for predicting transcription factor binding sites. 2012 IEEE International Conference on Cyber Technology in Automation, Control and Intelligent Systems (CYBER), 2012, 1:65-68 (EI) (web server) 23. Na R, Fan GL, Effect of the Corona Discharge on Peel Microstructure. 2011 International Conference on Materials for Renewable Energy & Environment[C]. Shanghai,China ，IEEE，2011, 1:2014-2017(EI, ISTP) 24. Fan GL, Li QZ, Predicting Protein Submitochondrion Location Using Pseudo-Average Chemical Shift and Hybrid Approach. International Biophysics Congress (17th IBC), 2011. 25. 樊国梁,张晓燕．自动跟踪太阳时角提高光伏发电效率[J]．澳门第一娱乐娱城官网学报, 2010,41(1): 116-119 26. 刘利,李前忠,樊国梁．低维输入空间的支持向量机识别人类剪接位点[J]．生物物理学报,2008,24(1):49-56 27. 陈颖丽,李前忠,樊国梁,杨科利．基于支持向量机的多类凋亡蛋白亚细胞位置预测[J],澳门第一娱乐娱城官网学报, 2008, 39(2): 159-165 28. 樊国梁,白凤山．EPP模式的DSP仿真器设计[J]．澳门第一娱乐娱城官网学报,2008, 39(3): 342-345 29. 陈颖丽,李前忠,杨科利,樊国梁．基于离散增量结合支持向量机方法的凋亡蛋白亚细胞位置预测[J]．生物物理学报2007,23(3):192-198 30. 杨乌日吐,李前忠,刘利,樊国梁．用支持向量机预测人类基因5′/3′选择性剪切位点[J]．现代生物医学进展,2007,7(5):790-795 31. 樊国梁,白凤山．基于DSP的频谱分析仪设计[J]．澳门第一娱乐娱城官网学报,2006, 37(4): 450-454 32. 樊国梁．基于VHDL的键盘扫描及显示电路设计[J]．电子世界, 2005, 26(2): 25-26. 33. 樊国梁．VHDL语言设计数字电路[J]．国外电子测量技术,2005,24(2):46-48. 34. 樊国梁．客户/服务器应用程序设计[J]．国外电子测量技术,2004,23(3):35-36. 35. 樊国梁．电话线防盗系统[J]．电子世界,2004,25(6):58-60. 36. 樊国梁．DELPHI中高精度时钟控件的设计[J]．国外电子测量技术，2003, 22(6): 33-35. 37. 樊国梁．一种月、季气候资料的处理使用方法[J]．内蒙古气象, 2003, 48(4): 30-34. 38. 樊国梁．在DELPHI中创建动态链接库DLL[J]．教学科研管理论文集,2002,6(1):31-33. |
